D-Dimer

D-Dimer is derived from cross-linked fibrin clot dissolved by plasmin. As long as there is activated thrombosis and fibrinolytic activity in the blood vessels of the body, D-dimer will increase. Its increase or positive is seen in secondary fibrinolytic hyperfunction, such as hypercoagulable state, diffuse intravascular coagulation, kidney disease, organ transplant rejection, thrombolytic therapy, etc. The phenomenon of elevated D-dimer due to diseases such as bacteremia can easily cause coagulation abnormalities, especially in the elderly and hospitalized patients.

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